Translational Research
From Bench to Bedside and Back Again in Pediatric Brain Injury Susan Margulies and her colleagues used to study a brain or lung injury in vivo in the lab and only record what happened. If an animal stopped breathing, they observed. If its blood pressure fell, they waited. But clinicians who are integral members of […]
Soul of Invention: Brian Litt’s Quest to Bring Moore’s Law to Therapeutic Devices
Though his work promises to transform medical care for the brain and heart, Brian Litt is motivated by a less scientific realm: his soul. Memories of patients with epilepsy whose lives were tragically altered by uncontrollable and unpredictable seizures drive Litt’s determination to find new therapeutics. Recalling, for example, the mother who drowned in the […]
Molecules that detect, monitor, and help to treat disease
On the third floor of Skirkanich Hall, Andrew Tsourkas is creating new magnetic nanoparticles that may revolutionize the detection of early cancer cells. By “early,” he means when molecular changes in the disease are occurring, but before any anatomical changes are visible. Detecting Cancer with Nanoparticles Today’s magnetic resonance imaging scans typically only reveal tumors […]